High genetic diversity among Mycobacterium tuberculosis strains in Tehran, Iran
نویسندگان
چکیده
منابع مشابه
Molecular Diversity of Mycobacterium tuberculosis Strains in Northwestern Iran
BACKGROUND Years after the development of antituberculosis (TB) drugs, many people continue to suffer from this disease. To control the spread of TB, strains of the Mycobacterium tuberculosis complex need to be determined, and sources of infection must be identified. Such steps should help to prevent transmission of the infection. OBJECTIVES The aim of this study was to perform molecular geno...
متن کاملMolecular diversity of Mycobacterium tuberculosis strains indifferent provinces of Iran
BACKGROUND AND OBJECTIVES Molecular epidemiology tools are widely used in determining epidemiology of tuberculosis. Spoligotyping is a molecular epidemiology method that is used for characterization and typing of Mycobacterium tuberculosis complex strains. The method is based on polymorphism of the chromosomal DR locus consisting of identical 36-bp DRs alternating with 35-41 unique spacers. The...
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The evolutionary history of the Mycobacterium tuberculosis complex (MTBC) has previously been studied by analysis of sequence diversity in extant strains, but not addressed by direct examination of strain genotypes in archaeological remains. Here, we use ancient DNA sequencing to type 11 single nucleotide polymorphisms and two large sequence polymorphisms in the MTBC strains present in 10 archa...
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Human tuberculosis caused by Mycobacterium tuberculosis (Mtb) remains a significant disease in many countries. According to Iran's borders with Afghanistan and Pakistan, which are among the 22 high burden countries around the world, this study was conducted to analyze the current molecular epidemiology of tuberculosis and survey genetic diversity of Mtb strains in Markazi Province in center of ...
متن کاملmolecular diversity of mycobacterium tuberculosis strains indifferent provinces of iran.
background and objectives: molecular epidemiology tools are widely used in determining epidemiology of tuberculosis. spoligotyping is a molecular epidemiology method that is used for characterization and typing of mycobacterium tuberculosis complex strains. the method is based on polymorphism of the chromosomal dr locus consisting of identical 36-bp drs alternating with 35-41 unique spacers. th...
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ژورنال
عنوان ژورنال: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
سال: 2018
ISSN: 2405-5794
DOI: 10.1016/j.jctube.2018.01.001